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Fundamental Investigation of the Adsorption of Antimicrobial Agents on Modified Calcium Carbonate and Silica and Its Potential Application in Food Packaging

Antimicrobial packaging has emerged as one of the most effective packaging systems in prolonging shelf life and maintaining food quality. For an effective system, a controlled and gradual release of antimicrobial agents into food items over time is crucial. Modified Calcium Carbonate (MCC), known for its diverse applications in pharmaceuticals and drug delivery, could act as a potential carrier for such agents in packaging. In this context, a fundamental study of the adsorption of two reference antimicrobial agents, Benzoic Acid (BA) and Thymol (TM), was carried on MCC and silica in solvents of different polarities. Based on the initial adsorption study, the adsorption isotherms of the two compounds were acquired by batch method in different solvents and then the adsorption data was modeled using adsorption isotherm models. Here, we found that n-Heptane was the most efficient solvent for both BA and TM on both adsorbents. From the outcome of the adsorption study, a model dispersion coating was prepared by mixing MCC (loaded with BA) with latex binder. Then the effect of latex binder on the rate of BA release from MMC was investigated by conducting desorption study using simulated body fluid as the desorbent solution at 4°C, comparing MCC with and without latex. It was found that the release rate of BA from our latex model dispersion coating was 31 time slower than that of MMC without latex. This indicates the potential application of our model dispersion coating in antimicrobial packaging.

Antimicrobial Packaging, Modified Calcium Carbonate, Silica, Benzoic Acid, Thymol, Adsorption, Desorption, Adsorbent

APA Style

Haseeb, A., Mesic, B., Samuelsson, J. (2024). Fundamental Investigation of the Adsorption of Antimicrobial Agents on Modified Calcium Carbonate and Silica and Its Potential Application in Food Packaging. Advances in Materials, 13(1), 1-9.

ACS Style

Haseeb, A.; Mesic, B.; Samuelsson, J. Fundamental Investigation of the Adsorption of Antimicrobial Agents on Modified Calcium Carbonate and Silica and Its Potential Application in Food Packaging. Adv. Mater. 2024, 13(1), 1-9. doi: 10.11648/

AMA Style

Haseeb A, Mesic B, Samuelsson J. Fundamental Investigation of the Adsorption of Antimicrobial Agents on Modified Calcium Carbonate and Silica and Its Potential Application in Food Packaging. Adv Mater. 2024;13(1):1-9. doi: 10.11648/

Copyright © 2023 Authors retain the copyright of this article.
This article is an open access article distributed under the Creative Commons Attribution License ( which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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