Volume 2, Issue 3, June 2013, Page: 42-47
Influence of Negative Poisson's Ratio on Stent Applications
S. K. Bhullar, Dept. of Mechanical Engineering, University of Victoria, Victoria, British Columbia,Canada
A. T. Mawanane Hewage, Institute for Materials Research & Innovation, University of Bolton, Deane Road, Bolton, U.K.
A. Alderson, Institute for Materials Research & Innovation, University of Bolton, Deane Road, Bolton, U.K.
K. Alderson, Institute for Materials Research & Innovation, University of Bolton, Deane Road, Bolton, U.K.
Martin B. G. Jun, Dept. of Mechanical Engineering, University of Victoria, Victoria, British Columbia,Canada
Received: Jun. 6, 2013;       Published: Jul. 20, 2013
DOI: 10.11648/j.am.20130203.14      View  3596      Downloads  273
Abstract
Stents are usually defined as small tubular structures that are inserted into the diseased region which provide mechanical support of damaged artery or some other hollow organ to restore lumen and blood flow conditions in arteries. Recently developed stents may accumulate functions; for example, they can be used for drug delivery or for treatment of bleeding esophageal varices. Further clinical failures such as crushing, removing, restenosis are some of the most serious reasons for continuing stent improvements. Therefore, our research study has the design and manufacture of an auxetic structure with enhanced mechanical properties through the tailored negative Poisson’s ratio, and its configuration as an auxetic stent to be used for example in the palliative treatment of esophageal cancer and for the prevention of dysphagia as the main objective. Background: The use of stents for esophageal diseases has evolved greatly over the past 30 years. Esophageal cancer is the growth of cancer cells in the esophagus tube which usually originates in the inner layers of the lining of the esophagus and grows outward. In time, the tumor can obstruct the passage of food and liquid, making swallowing painful and difficult. Since most patients are not diagnosed until the late stages of the disease, esophageal cancer is associated with poor quality of life and low survival rates. Method: This research study is organized in three parts devoted to fabrication of auxetic structure and stent samples, experimental testing and discussion of results. For this purpose a model of an auxetic rotating-square geometry with a circular hole structure is developed by laser cutting apolyurethane sheet. The auxeticoesophageal stent was made by folding and gluing the auxetic sheet (with rigid squares and circular holes) into a cylindrical shape. Combined videoextensometry with compressive and tensile testing are employed to determine the deformation response of the auxetic sheet and stent to obtain stress-strain curves and estimation of Poisson’s ratio.Conclusions: The stenting outcomes are improved through mechanical design with tailored negative Poisson’s ratio through cell geometry of the esophagus stent. Theauxetic stent geometry of rotating squares with circular holes will be lighter in weight; reduces obstruction and food impaction because of its unique deformation mechanism; and can reduces migration of the implant stent by embedding inside the tissue.
Keywords
Negative Poisson’s Ratio, AuxeticStents, Synclastic Property of Materials, Rotating Squares Geometry with Holes
To cite this article
S. K. Bhullar, A. T. Mawanane Hewage, A. Alderson, K. Alderson, Martin B. G. Jun, Influence of Negative Poisson's Ratio on Stent Applications, Advances in Materials. Vol. 2, No. 3, 2013, pp. 42-47. doi: 10.11648/j.am.20130203.14
Reference
[1]
Enzinger PC, Mayer RJ, "Esophageal cancer". N. Engl. J. Med. 2003,349 (23): 2241-52, doi:10.1056/NEJMra035010. PMID 14657432.
[2]
Shield W, Thomas. LoCicero, Joseph. B. Ponn, Ronald. Less Common Malignant Tumors of the Esophagus. Lippincott Williams & Wilkins 2005, pp. 2325-2340. ISBN 978-0-7817-3889-7.
[3]
Boyce HW Jr, Palliation of advanced esophageal cancer. SeminOncol 1984;11:186 .95.
[4]
Ahmed ME, Gustavson S. Current palliative modalities for esophageal car-cinoma. ActaChirScand 1990;156:95.8.
[5]
Tytgat GNJ. Endoscopic therapy of esophageal cancer: Possibilities and limitations. Endoscopy 1990;22:263.7.
[6]
Knyrim K, Wagner HJ, Bethge N, et al. A controlled trial of an expansile stent for palliation of esophageal obstruction due to inoperable cancer. N Engl J Med 1993;329:1302.7.
[7]
Homs MY, Steyerberg EW, Eijkenboom WM, et al. Single-dose brachytherapy versus metal stent placement for the palliation of dysphagia from oesophageal cancer: multicentrerandomised trial. Lancet 2004;364:1497-504.
[8]
Steyerberg EW, Homs MY, Stokvis A, et al. Stent placement or brachytherapy for palliation of dysphagia from esophageal cancer: a prognostic model to guide treatment selection. GastrointestEndosc 2005;62: 333-40.
[9]
Homs MY, Kuipers EJ, Siersema PD. Palliative therapy. J SurgOncol 2005;92:246-56.
[10]
Siersema PD. Treatment options for esophageal strictures. Nat ClinPractGastroenterolHepatol 2008;5:142-52.9
[11]
Costamagna G, Marchese M, Iacopini F. Self-expanding stents in oesophageal cancer. Eur J GastroenterolHepatol 2006;18:1177-80.
[12]
Mougey A, Adler DG. Esophageal stenting for the palliation of malignant dysphagia. J Support Oncol 2008;6:267-73.
[13]
Siersema PD, Marcon N, Vakil N. Metal stents for tumors of the distal esophagus and gastric cardia. Endoscopy 2003;35:79-85.
[14]
Saranovic D, Djuric-Stefanovic A, Ivanovic A, et al. Fluoroscopically guided insertion of self-expandable metal esophageal stents for palliative treatment of patients with malignant stenosis of esophagus and cardia: comparison of uncovered and covered stent types. Dis Esophagus 2005;18:230-8.
[15]
Conio M, Repici A, Battaglia G, et al. A randomized prospective comparison of self-expandable plastic stents and partially covered self-expandable metal stents in the palliation of malignant esophageal dysphagia. Am J Gastroenterol 2007;102:2667-77.
[16]
Stavroulakis GE. Auxeticbehaviour: appearance and engineering applications. Phys Status Solidi. 2005;242(3):710.20.
[17]
Lakes, RS,Foam structures with a negative Poisson's ratio. Science, 1987a,235: 1038-1040.
[18]
Lakes,RS.,Polyhedron cell structure and method of making same. Int. Patent.,1987b Publ. No. WO88/00523.
[19]
Lakes, RS.,Design considerations for negative Poisson's ratio materials. ASME J. Mech. Design, 1993a.115,.696-700.
[20]
Love, A.E. H., A Treatise on the Mathematical Theory of Elasticity, Dover, New York, NY, USA, 4th edition, Cambridge University Press,Cambridge,1927,163.
[21]
Veronda, DR.Westmann, RA. Mechanical characterization of skin finite deformations.,J.Biomech., 1970, 3, 111.124.
[22]
Frohlich, LM. LabarberaStevens,WP. Poisson.s ratio of a crossed fibre sheath: the skin of aquatic salamanders, J. Zool. Lond.,1994,232, 231.252.
[23]
Lees, C., Vincent, JEV.,Hillerton, JE., .Poisson.s ratio in skin., Biomed.Mater. Eng., 1991,1, 19.23.
[24]
Williams, JL. and Lewis, JL.Properties and an anisotropic model of cancellous bone from the proximal tibialepiphysis.Trans.ASME,J.Biomech. Eng.,1982,104, 5.56.
[25]
Liulan, L., Qingxi, H, Xianxu, H., Gaochun, X. .Design and Fabrication of Bone Tissue Engineering Scaxoolds via Rapid Prototyping and CAD., Journal of Rare Earths,2007, 25(2), 379.383.
[26]
Pan, Y., Dong, S., Hao, Y., Chu,T., Li, C., Zhang Z., Zhou,Y.,.Demineralized bone matrix gelatin as scaffold for tissue engineering., African Journal of Microbiology Research 2010, 4(9), 865-870.
[27]
Yang W, et al. Review on auxetic materials. J Mater Sci.2004;39:3269.79.
[28]
Gaspar N, et al. Quantitative analysis of the microscale of auxetic foams. Phys Status Solidi. 2005;242(2):550.60.
[29]
Alderson A, et al. Auxetic polymeric filters display enhanced defouling and pressure compensation properties. Membrane Technol. 2001;137:6.8.
[30]
Ali MN.Rehman IU. An Auxetic structure configured as oesophageal stent with potential to be used for palliative treatment of oesophageal cancer; development and in vitro mechanical analysis, J Mater Sci: Mater Med 2011, 22: DOI 10.1007/s10856-011-4436-y, pp. 2573–2581.
[31]
Grima JN, et al. Do zeolites have negative Poisson.s ratios? Adv Mater. 2000;12(24):1912.8.
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